Meanwhile, Caf has increased the prize money for the winners of Afcon from $7m (£5.2m) to $10m (£7.5m).
The surprise announcement about the future of Afcon was made by Motsepe after a meeting of Caf’s executive committee in Morocco before the start of the 2025 finals in Rabat on Sunday.
The biennial hosting of Afcon has long caused issues with the football calendar – with the vast majority of recent tournaments held midway through the European club season.
Caf had made a resolution for Afcon to be held in a June-July slot from 2019 onwards and began its new plan in Egypt that year.
But the Covid-19 pandemic and weather conditions in host nations in West Africa meant the 2021 and 2023 editions in Cameroon and Ivory Coast respectively were staged in January and February instead.
Fifa’s expanded 32-team Club World Cup was held in June and July this year, forcing Caf to opt for mid-season dates once again.
As a result this year’s Afcon in Morocco will take place over Christmas and the New Year for the first time, with the final on 18 January.
The dates for the finals in Kenya, Tanzania and Uganda in 2027 are yet to be announced, and that will be swiftly followed by another Afcon in 2028 – with the hosts of that edition yet to be decided.
After that, the continent’s biggest tournament will become a quadrennial tournament taking place in the same year as the European Championships.
Motsepe said the decision had been made in conjunction with Fifa president Gianni Infantino and the world governing body’s general secretary Mattias Grafstrom – and that Caf “have to compromise”.